The OrigAMI-3 Study
A study for people with colorectal cancer that has spread to other parts of the body (metastasized)
In order to qualify for the study, you’ll go through a screening process which may include blood tests, a CT or MRI of your tumor, and a physical exam.
You or your loved one CAN join the study if:
- You are over 18 years of age
- You have colorectal cancer that has come back or has spread to other parts of the body (metastatic)
- You have already completed a therapy for colorectal cancer
- You have laboratory test results showing your tumor or blood does not have any mutations (changes) in the following genes: KRAS, NRAS, or BRAF. If you are unsure whether your tumor or blood has any of these mutations, talk to the study doctor
You or your loved one CANNOT join the study if:
- You have cancer of the anal canal
- You are pregnant or breastfeeding
- You have an uncontrolled illness
- You have a diagnosis of persistent hypertension, congestive heart failure, deep vein thrombosis, or pulmonary embolism
The study includes the following parts:
Screening: Before you join a study, the study doctor and clinical staff will determine if you meet the specific requirements to participate. You will review and sign a document called an Informed Consent Form (ICF) that goes over the study details, as well as the potential risks and benefits of the study. You will also be able to ask any questions you have.
Treatment: If you qualify, you’ll receive an approved chemotherapy regimen for colorectal cancer. You will also receive the study medication OR an approved therapy for colorectal cancer. During this period, you will participate in regular visits and tests to see how you’re doing and how the study therapies are working.
Follow-up: Follow-up visits are done regularly and may be done at the office or on the phone. Follow-up visits help us collect useful information about the study medication.
Clinical research studies may help find better ways to treat different conditions. When people from all backgrounds participate in clinical research, it helps us understand how medicines affect people around the world who are impacted by certain conditions and diseases. Your participation can help shape the future of cancer care.
See if you may qualify
Answer the following questions to see if you or someone you know may be eligible to take part in this study.
Please keep in mind:
Even if you believe you meet the eligibility criteria, joining a clinical trial is not guaranteed. Whether you’re referred or able to take part depends on a review by a qualified healthcare professional.
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About your information:
With your consent, we will use your answers to help determine whether you may be eligible for this clinical trial. You can withdraw your consent at any time.
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